再说说达尔文的“近亲结婚悲剧”
29 11 2009年因为达尔文娶了他的表姐，所以有一个流传很广的谣言称，由于达尔文是近亲结婚，其子女不是夭折就是痴呆或短命。对此我已写过两篇文章澄清过（《达尔文的子女》、《达尔文一家十“院士”》）。华中农大动物科技学院老师朱猛进对此有不同看法：
“尽管与孟德尔同时代，但达尔文不懂遗传，造成了后人认为的近亲结婚的悲剧。达尔文与其表姐爱玛共生下了10个子女，其中3个夭折。就此问题方舟子曾有不同的观点，认为达尔文的子女夭折率和当时英国的平均夭折率没有差异，所以也就不存在达尔文近亲结婚的悲剧。不过，方舟子在推理上并不完全正确，因为当时的达尔文生活于上层社会，经济和医疗条件远远优于平均水平，他的子女夭折率与平均水平相当不具可比性，甚至在逻辑上反而说明其子女夭折率更高一点。当然，对于这件事确实有点强人所难，因为不只达尔文，同时代其他有名望的主流生物学家就没有一个人真正懂得遗传，这也是孟德尔生不逢时、临终前绝望呼喊‘我的时代一定会到来’的个人悲剧所在。”（朱猛进《被供上神坛的达尔文——《物种起源》发行150周年祭》）
达尔文虽然没能发现遗传规律，但他对遗传现象有很多认识，可能是当时掌握遗传知识最多的人。达尔文当然知道近亲结婚可能造成的危害，对达尔文家族和韦奇伍德家族如此频繁地表亲联姻（共有4对！）一直很担心，自己的子女夭折或生病也被他归咎于近亲结婚。所以说达尔文近亲结婚是因为“不懂遗传”，与事实不符。
但是近亲结婚会增加某些遗传疾病的概率，并不等于在实际上必然如此。我并不是简单地以夭折率来否定达尔文的“近亲结婚悲剧”，在《达尔文的子女》一文中还具体分析过达尔文的子女是怎么夭折的。下面就再重复一下其中的分析，看是否可能与近亲结婚有关。
达尔文的大女儿安妮（1841～1851）在10岁死于肺结核。肺结核是常见的传染病，在抗生素发明之前治疗它没有好办法，在当时是医院不予收治的不治之症，在死亡原因中排在第一位。因此她的死显然与近亲结婚无关。
达尔文的小儿子查尔斯（1856～1858）在2岁时死于猩红热。猩红热在当时对儿童是一种能够致命的常见传染病，同样生活于“上层社会”的托马斯·赫胥黎也有一个儿子三岁时死于猩红热。根据达尔文的记载以及查尔斯的照片判断，查尔斯的确患有遗传病，是唐氏综合征（俗称先天愚）患者。唐氏综合征主要与孕妇的年龄有关。爱玛生查尔斯时已是48岁的高龄产妇，而45岁以上的孕妇生下唐氏综合征婴儿的概率高达30分之1。显然，查尔斯的得病和死亡也与近亲结婚没有关系。
达尔文的二女儿玛丽（1842～1842）仅出生3周就死了。新生儿夭折率在当时是非常高的，大约五分之一的婴儿没能活到1岁。达尔文祖父伊拉兹马斯的10个子女，有3个都在婴儿时夭折：分别活了19天、4个月和不到1岁。伊拉兹马斯并没有近亲结婚。因此玛丽的夭折也不能归咎为近亲结婚。
达尔文没有夭折的两个女儿和五个儿子都很长寿，分别活了67、75、77、77、79、86、93岁。他们的智力都很正常，甚至高超，5个儿子都干出一番事业，3个成为王家学会会员。
我并不是在提倡近亲结婚。我只不过说，以达尔文的子女为例来说明近亲结婚的危害，是站不住脚的，不要再宣扬它了。
另外，朱猛进说孟德尔临终前绝望地呼喊“我的时代一定会到来”，也是夸大其词的。孟德尔对自己年轻时的研究成果并不那么有信心，在当上修道院院长后，就已放弃了科学研究，晚年的主要精力用在为了免税和政府扯皮，很难想像他在临终前突然心血来潮，像现在的科妄家一样高呼口号。在孟德尔死后很多年，在他被重新发现以后，才有一个他的朋友Gustav von Niessl回忆说孟德尔爱说“我的时代将会到来”（Meine Zeit wird schon kommen）——并非临终前的绝望呼喊。孟德尔是否真的说过这句话也是天晓得了，因为这位朋友当初在悼念孟德尔时，并没有提到这一句话。
“近亲结婚会增加某些遗传疾病的概率，并不等于在实际上必然如此。”
同意。
By the end of the 15th century 35
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Тема права и регуляторики в медицине остается одной из самых актуальных. Особенно это касается врачебных ошибок и их последствий. ответственность медицинских работников правила регистрации медицинских изделий Не менее важно понимать как регулируется обращение лекарственных средств по ФЗ 61. Без этого невозможно представить современную медицину.
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Искал варианты кухонь на днях и обнаружил множество предложений в городе. Особенно понравились кухни Gloria — материалы не подкачало. Между прочим когда изучал кухни глория спб убедился что это входят в топ по соотношению цена/качество. К тому же компания гарантирует хорошую гарантию что немало важно. Если решитесь приобрести гарнитур рекомендую этого производителя.
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Затеял ремонт и столкнулся с вопросом какую кухню выбрать. В Питере очень много магазинов но хотелось что-то индивидуальное. В итоге остановился на каталог кухонь под заказ — там оказался удобный подбор по размерам и стилю. Оценил что можно сделать 3D-визуализацию перед заказом. Для СПб это оказалось лучшим вариантом. Советую посмотреть их каталог если хотите сделать всё под ключ с дизайн-проектом.
Обратился в «Глория» за кухней на заказ — результат превзошёл ожидания. Мастера учли все пожелания и стоимость меня приятно удивила. Когда искал кухни СПб на заказ советую обратить внимание на заказать кухню спб — там можно найти отличные варианты. «Глория» — одна из лучших компаний в СПб с доступными ценами и высоким качеством. Рекомендую их всем друзьям.
Здравствуйте Думаю стоит обсудить своим опытом по поводу дистанционного обучения. Выбор действительно огромен и легко запутаться. Мы с ребёнком долго искали нужный вариант — пересмотрели кучу сайтов. В итоге остановились на LBS — это надёжная школа для дистанционного обучения. Кстати когда искали информацию наткнулись на обучение в онлайн школе для школьников — оказалось ценные советы. Занятия проходят достаточно комфортно преподаватели профессиональные. Планируете онлайн-образование рекомендую посмотреть данную школу. Моему ребёнку идеально подошло
Хочу заказать новую кухню посоветуйте хороший вариант в Питере. Перерыл кучу сайтов но всё как-то сомнительно. Вот думаю где правильнее купить кухню на заказ СПб — каталог кухонных гарнитуров на заказ находил достойные исполнения но стоит ли доверять. Как насчёт сроков изготовления — долго ждать? Жду ваших рекомендаций.
Расскажу как я выбирал кухню на заказ в СПб — может кому-то пригодится. Пересмотрел кучу вариантов и в итоге остановился на недорогой кухне в рассрочку. Главное — не торопиться с выбором. В процессе поиска наткнулся на кухни под заказ каталог СПб https://zakazat-kuhnyu-avq.ru — там оказалось удобный каталог с 3D-проектами. Очень рекомендую посмотреть этот вариант если хотите выбрать что-то нестандартное. В итоге остался доволен результатом. Могу поделиться контактами.
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Trial didnt describe number of participantswith minimal/overt hepatic encephalopathy Participant traits: not reported Interventions L-ornithine L-aspartate: oral 18 g/day Control: oral placebo not speci?ed Duration of remedy: 7 days Cointerventions: none reported Outcomes Outcomes included in meta-analyses: none Country Indonesia Neuropsychiatric assessment � Mental status � Critical Flicker Frequency � Blood ammonia Inclusion period Not reported Notes Publication status: summary Unpublished info: requested however none received L-ornithine L-aspartate for prevention and remedy of hepatic encephalopathy in people with cirrhosis Review fifty six Copyright � 2018 The Cochrane Collaboration. Providing testing companies for other countries Private laboratories in Brazil China Egypt India and South Africa are offering providers for other international locations principally for neighbouring international locations with a much less developed testing service infrastructure. 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